It is most common in people in their second to third decades but can be seen at almost any age. The calcifying odontogenic cyst coc is a simple cyst lined by ameloblastomalike epithelium with ghost cells. This decompression facilitates a reduction in the size of the cyst and so, at a later an odontogenic cyst is a pathological. Jun 07, 20 may can produce expansion of the cortical bone. The calcifying odontogenic cyst coc is a benign odontogenic cyst that occurs in the gnathic bones. The radiolucency may be unilocular or multilocular. The full text of this article is available as a pdf 487k.
The calcifying ghost cell odontogenic tumor or the. An 11yearold female patient presented a swelling in the vestibular. Ameloblastoma,myxoma and odontogenic fibroma are the commonest neoplasms. A dentigerous cyst results because of the enlargement of the follicular space of the whole or part of the crown of an impacted or unerupted tooth and is attached to the neck of the tooth. Calcifying odontogenic cyst calcifying cystic odontogenic tumor calcifying odontogenic cyst was initially described by gorlin and colleagues 283 in 1962 as a possible oral analogue to malherbes calcifying epithelioma pilomatricoma of the skin, owing to the presence of ghost cell keratinization in both lesions. Most of the cells were anuclear or contained pyknotic nuclei. Kramer 1974 has defined a cyst as a pathological cavity having fluid, semifluid or gaseous contents and which is not created by the accumulation of pus. Dentigerous cysts are developmental odontogenic jaw cysts.
Pdf introduction calcifying odontogenic cysts coc represent 0. According to the current 2005 classification of the world health organization, both parakeratizied odontogenic keratocyst and calcifying odotogenic cyst have neoplastic characteristics, thus renamed as keratocystic odontogenic tumor and calcifying odotogenic tumor, respectively. Calcifying cystic odontogenic tumor ccot is an uncommon odontogenic tumor. The opening can also be maintained with packing material or a prosthetic bung. Synchronization of calcifying odontogenic cyst and aneurysmal bone cyst. Although the condition is often described as being cystic 85% of the cases, a significant percentage of calcifying odontogenic cysts grow as more solid, seemingly neoplastic proliferations, and the term dentinogenic ghost cell tumor has been used to describe these lesions. The odontogenic cysts are a diverse groups of odontogenic lesions of the jaws the radicular cyst is an inflammatory lesion, and although by far the most common, it is clinically easy to diagnose and manage other cysts are less frequently encountered and some e. Calcifying ghost cell odontogenic cyst cgcoc is a heterogeneous group of lesion existing either as cystic or solid variant. It could be concluded, that the group contained two entities, a cyst and a neoplasm. Also called as odontogenic ghost cell cyst or gorlin cyst. Although rare, because of its variable presentation calcifying cystic odontogenic tumor should be included in the differential diagnosis of jaw lesions. Calcifying epithelial odontogenic tumor an overview.
It was first reported as a separate pathologic entity by gorlinet al in 1962 as a likely analog of the cutaneous calcifyingepithelioma of malherbe or pilomatricoma. The calcifying odontogenic cyst coc was first recognised as a distinct pathological entity by gorlin et al 1 in 1962. Recurrent calcifying odontogenic cyst universiteit utrecht. Why is its differentiation from other types of cysts important.
However, a clinical study with larger number of cases and longterm followup is required. Coc is a rare odontogenic lesion with variable clinicohistological characteristics. Calcifying odontogenic cyst gorlins cyst report of two cases. The calcifying odontogenic cyst is an uncommon benign cyst of odontogenic origin, characterized by an ameloblastomalike epithelium with ghost cells that may. It is an unusual and unique lesion, which may show characteristics of both a solid neoplasm and a cyst. On a radiograph, the radiolucency of a cyst is usually bordered by a radiopaque periphery of dense sclerotic bone. Introduction calcifying odontogenic cyst coc or calcifying cystic odontogenic tumor ccot is one of the ghost cell odontogenic lesions that mostly grows as a cystic lesion. The pathological changes associated with the impacted 3rd molar are cystic changes which include dentigerous cysts, odontogenic keratocyst and calcifying odontogenic cyst. The unilocular radiolucency is well demarcated with smooth cortical border.
The calcifying odontogenic cyst coc, described separately by gorlin et al in 1962 and by gold2 in 1963, is derived from odontogenic epithelial remnants within the mandible or maxilla, or from the gingiva. Calcifying odontogenic cyst coc, first described as a separate entity by gorlin et al. Dentigerous cyst odontogenic keratocyst orthokeratinized odontogenic cyst gingival alveolar cyst of the newborn gingival cyst of the adult lateral periodontal cyst calcifying odontogenic gorlin cyst glandular odontogenic cyst eruption cyst cyst lumen lining epithelium. Synchronization of calcifying odontogenic cyst and aneurysmal. Areas of an eosinophilic matrix material compatible dentinoid also may present adjacent to the epithelial component. On radiographs, the calcifying odontogenic cyst appears as a unilocular radiolucency dark area. Calcifying odontogenic cyst with atypical features ncbi. Calcifying odontogenic cyst coc or calcifying cystic odontogenic tumor was first introduced in 1962 by gorlin et al. The calcifying odontogenic cyst a possible analogue of the cutaneous calcifying epitherlioma of malherb.
Calcifying odontogenic cyst rajkumar k, kamal k, sathish m r. Calcifying odontogenic cyst ishwar singh, 1 lata gathwala, 2 rohit sharma, 3 h. Calcifying odontogenic cyst free download as powerpoint presentation. Oct 16, 2010 the peripheral calcifying odontogenic cyst pcoc accounts for less than 25% of the cases of calcifying odontogenic cysts and most commonly appears as a nodule on the gingiva. Calcifying odontogenic cyst is a rare and specific lesion with properties of a tumor that can appear anywhere on the body and have properties of a cyst. Apr 22, 20 the calcifying odontogenic cyst gorlin cyst.
Recurrent calcifying odontogenic cyst 145 have been reported in the literature, one by gorlin et al. Odontogenic cysts are those which arise from the epithelium associated with the development of teeth. In 2005, coc was classified as a tumour and designated as a calcifying. In 1962, gorlin described a rare cystic form termed the calcifying odontogenic cyst coc or. Gold originally termed the lesion keratinizing and. Calcifying cystic odontogenic tumor ccot previously knownas calcifying odontogenic cyst coc is a relatively rare lesion. Calcifying cystic odontogenic tumor accompanied by a dentigerous. Ky why is an odontogenic keratocyst often difficult to diagnose. Soft tissue pathological changes are hyperplasias,inflammation and calcification are the common findings around the impacted 3rd molar teeth. Most lesions are pericoronal, juxta coronal, and divergence of roots and displacement of teeth often occurs without root resorption 23, 10,11. There are only four cases of coc with af cited in the english literature. Calcifying odontogenic cyst synonyms, calcifying odontogenic. Odontogenic keratocysts are often difficult to diagnose because they may occur in many. Calcifying odontogenic cyst or gorlin cyst, was first described by gorlin.
Because of thediverse clinicohistologic features and the various neoplasticpotential, there have been. The paper reports on two new cases of calcifying odontogenic cysts, and gives a survey of 50 cases reported in the literature. The aim of this study was to integrate the available data published on calcifying odontogenic cyst coc, dentinogenic ghost cell tumor dgct, and ghost cell odontogenic carcinomas gcocs into a comprehensive analysis of their clinicoradiological features, treatment, and recurrence. Calcifying odontogenic cyst, dentinogenic ghost cell tumor. Although it is a rare event, odontogenic tumors such as ameloblastoma, ameloblastic fibroma af, ameloblastic fibroodontoma, and odontoma have been reported associated with calcifying odontogenic cyst coc. Different manifestations of calcifying cystic odontogenic tumor. J oral maxillofac surg calcifying odon togenic cyst. The calcifying cystic odontogenic tumor can occur in any location of the oral cavity and approximately 6567. Case report ameloblastomatous calcifying odontogenic cyst. Histologically, ccot is usually composed of a cystic cavity with fibrotic capsule lined by an odontogenic epithelium. This obviously requires a compliant and dextrous patient who would be able to maintain hygiene. Coc is a rare disorder of the jaw 2, and the reported frequency of cocs varies from 0. Clinically, cgcoc may present either as central 85% or peripheral lesion 15%.
Scribd is the worlds largest social reading and publishing site. Calcifying odotogenic cyst is a benign odontogenic tumor of cystic type most likely to affect the anterior areas of the jaws. Since the original description of the calcifying odontogenic cyst by gorlin et al. The calcifying odontogenic cyst or gorlin cyst was originally identified as an independent condition by gorlin in 1962 year.
Synonyms for calcifying odontogenic cyst in free thesaurus. The calcifying odontogenic cyst coc was first delineated in 1962. The peripheral coc is a rare lesion and few reports have been published considering its clinical and histopatholo. It was previously described by gorlin et al in 1962 as a calcifying odontogenic cyst. Pdf calcifying cystic odontogenic tumor with compound. Different manifestations of calcifying cystic 367 einstein. Jul 24, 2010 the world health organization classification of head and neck tumors classifies the lesion as an odontogenic tumor and names it calcifying cystic odontogenic tumor. In one case the ultrastructure of the characteristic ghost cells was examined. Even the cystic lesion has apparent neoplastic potential but most. Calcifying odontogenic cyst with ameloblastic fibroma. Calcifying odontogenic cyst definition of calcifying. Calcifying odontogenic cyst with extensive areas of dentinoid. The world health organization who classified 2005 coc as a neoplasm and used the term calcifying cystic odontogenic tumor ccot for.
Pdf calcifying epithelial odontogenic cyst of the mandible. The calcifying odontogenic cyst gorlin cyst pure facts. Sep 30, 2012 lateral periodontal cyst glandular odontogenic cyst unclassified paradental cyst calcifying odontogenic cyst 9. It is a rare developmental odontogenic cyst with notable presence of histopathological. Has many features of odontogenic tumor, therefore it is placed in the category of tumors in the latest who classification of odontogenic cysts and tumors. Calcifying epithelial odontogenic tumor of the maxilla.
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